Induction of autoimmunity by immunization with hapten-modified hen egg lysozyme in hen egg lysozyme-transgenic mice

To understand the mechanism of autoimmunity induction, hen egg lysozyme (HEL)-transgenic (Tg) C57BL/6 (B6) mice were immunized with HEL or phosphorylcholine-conjugated HEL (PC-HEL). Repeated immunization of HEL-Tg mice with native HEL failed to induce the antibody response against HEL. However, immu...

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Bibliographic Details
Main Authors: Kang, Hee-Kap, Chung, Yun Jo, Park, Chung Ung, Jang, Yong-Suk, Kim, Byung S
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2006
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782231/
https://ncbi.nlm.nih.gov/pubmed/16476056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2005.02310.x
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