Neuroligin-4 regulates excitatory synaptic transmission in human neurons

The autism-associated synaptic-adhesion gene Neuroligin-4 (NLGN4) is poorly conserved evolutionarily, limiting conclusions from Nlgn4 mouse models for human cells. Here, we show that the cellular and subcellular expression of human and murine Neuroligin-4 differ, with human Neuroligin-4 primarily ex...

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Publicado en:Neuron
Autores principales: Marro, Samuele G., Chanda, Soham, Yang, Nan, Janas, Justyna A., Valperga, Giulio, Trotter, Justin, Zhou, Bo, Merrill, Sean, Yousif, Issa, Shelby, Hannah, Vogel, Hannes, Kalani, M. Yashar S., Südhof, Thomas C., Wernig, Marius
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6706319/
https://ncbi.nlm.nih.gov/pubmed/31257103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2019.05.043
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