Neuroligin-4 regulates excitatory synaptic transmission in human neurons

The autism-associated synaptic-adhesion gene Neuroligin-4 (NLGN4) is poorly conserved evolutionarily, limiting conclusions from Nlgn4 mouse models for human cells. Here, we show that the cellular and subcellular expression of human and murine Neuroligin-4 differ, with human Neuroligin-4 primarily ex...

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Publicado en:Neuron
Main Authors: Marro, Samuele G., Chanda, Soham, Yang, Nan, Janas, Justyna A., Valperga, Giulio, Trotter, Justin, Zhou, Bo, Merrill, Sean, Yousif, Issa, Shelby, Hannah, Vogel, Hannes, Kalani, M. Yashar S., Südhof, Thomas C., Wernig, Marius
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6706319/
https://ncbi.nlm.nih.gov/pubmed/31257103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2019.05.043
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