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An Autism-Associated Mutation Impairs Neuroligin-4 Glycosylation and Enhances Excitatory Synaptic Transmission in Human Neurons

Neuroligins (NLGNs) are a class of postsynaptic cell adhesion molecules that interact with presynaptic neurexins (NRXNs) and regulate synapse function. NLGN4 is a member of the NLGN family and consists of a unique amino acid sequence in humans that is not evolutionarily well conserved in rodents. Th...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Cast, Thomas P., Boesch, Daniel J., Smyth, Kim, Shaw, Alisa E., Ghebrial, Michael, Chanda, Soham
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7821862/
https://ncbi.nlm.nih.gov/pubmed/33268543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0404-20.2020
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