TOM1 Regulates Neuronal Accumulation of Amyloid-β Oligomers by FcγRIIb2 Variant in Alzheimer's Disease

Emerging evidences suggest that intraneuronal Aβ correlates with the onset of Alzheimer's disease (AD) and highly contributes to neurodegeneration. However, critical mediator responsible for Aβ uptake in AD pathology needs to be clarified. Here, we report that FcγRIIb2, a variant of Fcγ-recepto...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Gwon, Youngdae, Kam, Tae-In, Kim, Seo-Hyun, Song, Sungmin, Park, Hyejin, Lim, Bitna, Lee, Haneul, Lee, Weontae, Jo, Dong-Gyu, Jung, Yong-Keun
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6705977/
https://ncbi.nlm.nih.gov/pubmed/30185465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1996-17.2018
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