FcγRIIb mediates amyloid-β neurotoxicity and memory impairment in Alzheimer’s disease

Amyloid-β (Aβ) induces neuronal loss and cognitive deficits and is believed to be a prominent cause of Alzheimer’s disease (AD); however, the cellular pathology of the disease is not fully understood. Here, we report that IgG Fcγ receptor II-b (FcγRIIb) mediates Aβ neurotoxicity and neurodegeneratio...

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Detalhes bibliográficos
Main Authors: Kam, Tae-In, Song, Sungmin, Gwon, Youngdae, Park, Hyejin, Yan, Ji-Jing, Im, Isak, Choi, Ji-Woo, Choi, Tae-Yong, Kim, Jeongyeon, Song, Dong-Keun, Takai, Toshiyuki, Kim, Yong-Chul, Kim, Key-Sun, Choi, Se-Young, Choi, Sukwoo, Klein, William L., Yuan, Junying, Jung, Yong-Keun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696552/
https://ncbi.nlm.nih.gov/pubmed/23921129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66827
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