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Deletion of the Cold Thermoreceptor TRPM8 Increases Heat Loss and Food Intake Leading to Reduced Body Temperature and Obesity in Mice

The coupling of energy homeostasis to thermoregulation is essential to maintain homeothermy in changing external environments. We studied the role of the cold thermoreceptor TRPM8 in this interplay in mice of both sexes. We demonstrate that TRPM8 is required for a precise thermoregulation in respons...

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Bibliografische gegevens
Gepubliceerd in:J Neurosci
Hoofdauteurs: Reimúndez, Alfonso, Fernández-Peña, Carlos, García, Guillermo, Fernández, Rubén, Ordás, Purificación, Gallego, Rosalía, Pardo-Vazquez, Jose L., Arce, Victor, Viana, Félix, Señarís, Rosa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6705917/
https://ncbi.nlm.nih.gov/pubmed/29530988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3002-17.2018
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