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Modulation of Thermoreceptor TRPM8 by Cooling Compounds

[Image: see text] ThermoTRPs, a subset of the Transient Receptor Potential (TRP) family of cation channels, have been implicated in sensing temperature. TRPM8 and TRPA1 are both activated by cooling. TRPM8 is activated by innocuous cooling (<30 °C) and contributes to sensing unpleasant cold stimu...

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Autori principali: Bharate, Sonali S., Bharate, Sandip B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2012
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369806/
https://ncbi.nlm.nih.gov/pubmed/22860192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn300006u
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