Antimicrobial Agent Triclosan Disrupts Mitochondrial Structure, Revealed by Super-resolution Microscopy, and Inhibits Mast Cell Signaling via Calcium Modulation

The antimicrobial agent triclosan (TCS) is used in products such as toothpaste and surgicalsoaps and is readily absorbed into oral mucosa and human skin. These and many other tissues contain mast cells, which are involved in numerous physiologies and diseases. Mast cells release chemical mediators t...

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Bibliografiske detaljer
Udgivet i:Toxicol Appl Pharmacol
Main Authors: Weatherly, Lisa M., Nelson, Andrew J., Shim, Juyoung, Riitano, Abigail M., Gerson, Erik D., Hart, Andrew J., de Juan-Sanz, Jaime, Ryan, Timothy A., Sher, Roger, Hess, Samuel T., Gosse, Julie A.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6705416/
https://ncbi.nlm.nih.gov/pubmed/29630968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2018.04.005
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