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A Microplate Assay to Assess Chemical Effects on RBL-2H3 Mast Cell Degranulation: Effects of Triclosan without Use of an Organic Solvent

Mast cells play important roles in allergic disease and immune defense against parasites. Once activated (e.g. by an allergen), they degranulate, a process that results in the exocytosis of allergic mediators. Modulation of mast cell degranulation by drugs and toxicants may have positive or adverse...

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Detalhes bibliográficos
Main Authors: Weatherly, Lisa M., Kennedy, Rachel H., Shim, Juyoung, Gosse, Julie A.
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969050/
https://ncbi.nlm.nih.gov/pubmed/24300285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/50671
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