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Antimicrobial Agent Triclosan is a Proton Ionophore Uncoupler of Mitochondria in Living Rat and Human Mast Cells and in Primary Human Keratinocytes

Triclosan (TCS) is an antimicrobial used widely in hospitals and personal care products, at ~10 mM. Human skin efficiently absorbs TCS. Mast cells are ubiquitous key players both in physiological processes and in disease, including asthma, cancer, and autism. We previously showed that non-cytotoxic...

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Bibliografske podrobnosti
izdano v:J Appl Toxicol
Main Authors: Weatherly, Lisa M., Shim, Juyoung, Hashmi, Hina N., Kennedy, Rachel H., Hess, Samuel T., Gosse, Julie A.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724348/
https://ncbi.nlm.nih.gov/pubmed/26204821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jat.3209
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