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Mechanism of uncoupling in mitochondria: uncouplers as ionophores for cycling cations and protons.

Classical uncouplers such as 2,4-dinitrophenol have been shown to be ionophores with the capability for transporting monovalent or divalent cations with equal efficiency. The conditions appropriate for the maximal expression of this ionophoric capability have been explored. Two critical factors are...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kessler, R J, Tyson, C A, Green, D E
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1976
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430958/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9641/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.9.3141
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