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Mechanism of uncoupling in mitochondria: uncouplers as ionophores for cycling cations and protons.
Classical uncouplers such as 2,4-dinitrophenol have been shown to be ionophores with the capability for transporting monovalent or divalent cations with equal efficiency. The conditions appropriate for the maximal expression of this ionophoric capability have been explored. Two critical factors are...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1976
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430958/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9641/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.9.3141 |
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