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Delivery of siRNA therapeutics using cowpea chlorotic mottle virus-like particles

While highly promising in medicine, gene therapy requires delivery agents to protect and target nucleic acid therapeutics. We developed a plant viral siRNA delivery platform making use of self-assembling cowpea chlorotic mottle virus (CCMV). CCMV was loaded with siRNAs targeting GFP or FOXA1; to fur...

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Detalhes bibliográficos
Publicado no:Biomater Sci
Main Authors: Lam, Patricia, Steinmetz, Nicole F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6705399/
https://ncbi.nlm.nih.gov/pubmed/31257379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9bm00785g
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