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MELD × MD Folds Nonthreadables, Giving Native Structures and Populations

A current challenge is to compute the native structures of proteins from their amino acid sequences. A main approach of bioinformatics is threading, in which a protein to be predicted is computationally threaded onto protein fragments of similar sequence having an already known structure. However, ~...

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Bibliografske podrobnosti
izdano v:J Chem Theory Comput
Main Authors: Robertson, James C., Perez, Alberto, Dill, Ken A.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6705390/
https://ncbi.nlm.nih.gov/pubmed/30407805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.8b00886
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