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Toxic properties of microsome-associated alpha-synuclein species in mouse primary neurons.
α-synuclein (αS) is a small protein that self-aggregates into α-helical oligomer species and subsequently into larger insoluble amyloid fibrils that accumulate in intraneuronal inclusions during the development of Parkinson’s disease. Toxicity of αS oligomers and fibrils has been long debated and mo...
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| 發表在: | Neurobiol Dis |
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| Main Authors: | , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6705388/ https://ncbi.nlm.nih.gov/pubmed/29246724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2017.12.004 |
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