Spinal Serum-Inducible and Glucocorticoid-Inducible Kinase 1 Mediates Neuropathic Pain via Kalirin and Downstream PSD-95-Dependent NR2B Phosphorylation in Rats

The coupling of the spinal postsynaptic density-95 (PSD-95) with the glutamatergic N-methyl-d-aspartate receptor NR2B subunit and the subsequent NR2B phosphorylation contribute to pain-related plasticity. Increasing evidence reveals that kalirin, a Rho-guanine nucleotide exchange factor, modulates P...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Peng, Hsien-Yu, Chen, Gin-Den, Lai, Cheng-Yuan, Hsieh, Ming-Chun, Lin, Tzer-Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6704989/
https://ncbi.nlm.nih.gov/pubmed/23516288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4452-12.2013
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