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Spinal TNF-α impedes Fbxo45-dependent Munc13-1 ubiquitination to mediate neuropathic allodynia in rats

Presynaptic active zone proteins play a crucial role in regulating synaptic plasticity. Although the ubiquitin–proteasome system underlying the degradation of the presynaptic active zone protein is well established, the contribution of this machinery to regulating spinal plasticity during neuropathi...

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Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Hsieh, Ming-Chun, Ho, Yu-Cheng, Lai, Cheng-Yuan, Chou, Dylan, Chen, Gin-Den, Lin, Tzer-Bin, Peng, Hsien-Yu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057957/
https://ncbi.nlm.nih.gov/pubmed/30042425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0859-4
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