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Spinal TNF-α impedes Fbxo45-dependent Munc13-1 ubiquitination to mediate neuropathic allodynia in rats

Presynaptic active zone proteins play a crucial role in regulating synaptic plasticity. Although the ubiquitin–proteasome system underlying the degradation of the presynaptic active zone protein is well established, the contribution of this machinery to regulating spinal plasticity during neuropathi...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Hsieh, Ming-Chun, Ho, Yu-Cheng, Lai, Cheng-Yuan, Chou, Dylan, Chen, Gin-Den, Lin, Tzer-Bin, Peng, Hsien-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057957/
https://ncbi.nlm.nih.gov/pubmed/30042425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0859-4
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