Spinal RNF20-Mediated Histone H2B Monoubiquitylation Regulates mGluR5 Transcription for Neuropathic Allodynia

To date, histone H2B monoubiquitination (H2Bub), a mark associated with transcriptional elongation and ongoing transcription, has not been linked to the development or maintenance of neuropathic pain states. Here, using male Sprague Dawley rats, we demonstrated spinal nerve ligation (SNL) induced be...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Lai, Cheng-Yuan, Hsieh, Ming-Chun, Ho, Yu-Cheng, Wang, Hsueh-Hsiao, Chou, Dylan, Wen, Yang-Cheng, Yang, Po-Sheng, Cheng, Jen-Kun, Peng, Hsien-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2018
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6705988/
https://ncbi.nlm.nih.gov/pubmed/30201771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1069-18.2018
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