Spinal RNF20-Mediated Histone H2B Monoubiquitylation Regulates mGluR5 Transcription for Neuropathic Allodynia

To date, histone H2B monoubiquitination (H2Bub), a mark associated with transcriptional elongation and ongoing transcription, has not been linked to the development or maintenance of neuropathic pain states. Here, using male Sprague Dawley rats, we demonstrated spinal nerve ligation (SNL) induced be...

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Pubblicato in:J Neurosci
Autori principali: Lai, Cheng-Yuan, Hsieh, Ming-Chun, Ho, Yu-Cheng, Wang, Hsueh-Hsiao, Chou, Dylan, Wen, Yang-Cheng, Yang, Po-Sheng, Cheng, Jen-Kun, Peng, Hsien-Yu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2018
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6705988/
https://ncbi.nlm.nih.gov/pubmed/30201771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1069-18.2018
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