Deletion of Abca7 Increases Cerebral Amyloid-β Accumulation in the J20 Mouse Model of Alzheimer's Disease

ATP-binding cassette transporter A7 (ABCA7) is expressed in the brain and has been detected in macrophages, microglia, and neurons. ABCA7 promotes efflux of lipids from cells to apolipoproteins and can also regulate phagocytosis and modulate processing of amyloid precursor protein (APP) to generate...

Full description

Saved in:
Bibliographic Details
Published in:J Neurosci
Main Authors: Kim, Woojin S., Li, Hongyun, Ruberu, Kalani, Chan, Sharon, Elliott, David A., Low, Jac Kee, Cheng, David, Karl, Tim, Garner, Brett
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2013
Subjects:
Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6704948/
https://ncbi.nlm.nih.gov/pubmed/23467355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4165-12.2013
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items