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Perturbation of neuronal cobalamin transport by lysosomal enzyme inhibition

Cbl (cobalamin) utilization as an enzyme cofactor is dependent on its efficient transit through lysosomes to the cytosol and mitochondria. We have previously proposed that pathophysiological perturbations in lysosomal function may inhibit intracellular Cbl transport with consequences for down-stream...

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Detalhes bibliográficos
Main Authors: Zhao, Hua, Ruberu, Kalani, Li, Hongyun, Garner, Brett
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908614/
https://ncbi.nlm.nih.gov/pubmed/27919045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20130130
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