Disruption of the Presynaptic Cytomatrix Protein Bassoon Degrades Ribbon Anchorage, Multiquantal Release, and Sound Encoding at the Hair Cell Afferent Synapse

Inner hair cells (IHCs) of the cochlea use ribbon synapses to transmit auditory information faithfully to spiral ganglion neurons (SGNs). In the present study, we used genetic disruption of the presynaptic scaffold protein bassoon in mice to manipulate the morphology and function of the IHC synapse....

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Bibliografiset tiedot
Julkaisussa:J Neurosci
Päätekijät: Jing, Zhizi, Rutherford, Mark A., Takago, Hideki, Frank, Thomas, Fejtova, Anna, Khimich, Darina, Moser, Tobias, Strenzke, Nicola
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2013
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6704940/
https://ncbi.nlm.nih.gov/pubmed/23467361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3491-12.2013
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