Deficiency and haploinsufficiency of histone macroH2A1.1 in mice recapitulate hematopoietic defects of human myelodysplastic syndrome

BACKGROUND: Epigenetic regulation is important in hematopoiesis, but the involvement of histone variants is poorly understood. Myelodysplastic syndromes (MDS) are heterogeneous clonal hematopoietic stem cell (HSC) disorders characterized by ineffective hematopoiesis. MacroH2A1.1 is a histone H2A var...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Bereshchenko, Oxana, Lo Re, Oriana, Nikulenkov, Fedor, Flamini, Sara, Kotaskova, Jana, Mazza, Tommaso, Le Pannérer, Marguerite-Marie, Buschbeck, Marcus, Giallongo, Cesarina, Palumbo, Giuseppe, Li Volti, Giovanni, Pazienza, Valerio, Cervinek, Libor, Riccardi, Carlo, Krejci, Lumir, Pospisilova, Sarka, Stewart, A. Francis, Vinciguerra, Manlio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6704528/
https://ncbi.nlm.nih.gov/pubmed/31439048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-019-0724-z
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados