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Ouabain-regulated phosphoproteome reveals molecular mechanisms for Na(+), K(+)–ATPase control of cell adhesion, proliferation, and survival
The ion pump Na(+), K(+)–ATPase (NKA) is a receptor for the cardiotonic steroid ouabain. Subsaturating concentration of ouabain triggers intracellular calcium oscillations, stimulates cell proliferation and adhesion, and protects from apoptosis. However, it is controversial whether ouabain-bound NKA...
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| Veröffentlicht in: | FASEB J |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Federation of American Societies for Experimental Biology
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6704450/ https://ncbi.nlm.nih.gov/pubmed/31199885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201900445R |
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