Exhaustion of CD4+ T-cells mediated by the Kynurenine Pathway in Melanoma

Kynurenine pathway (KP) activation by the enzymatic activity of indoleamine 2,3-dioxygenase1 (IDO1) and kynurenine (KYN) production represents an attractive target for reducing tumour progression and improving anti-tumour immunity in multiple cancers. However, immunomodulatory properties of other KP...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Rad Pour, Soudabeh, Morikawa, Hiromasa, Kiani, Narsis A., Yang, Muyi, Azimi, Alireza, Shafi, Gowhar, Shang, Mingmei, Baumgartner, Roland, Ketelhuth, Daniel F. J., Kamleh, Muhammad Anas, Wheelock, Craig E., Lundqvist, Andreas, Hansson, Johan, Tegnér, Jesper
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6704156/
https://ncbi.nlm.nih.gov/pubmed/31434983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48635-x
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados