Immunometabolic Network Interactions of the Kynurenine Pathway in Cutaneous Malignant Melanoma

Dysregulation of the kynurenine pathway has been regarded as a mechanism of tumor immune escape by the enzymatic activity of indoleamine 2, 3 dioxygenase and kynurenine production. However, the immune-modulatory properties of other kynurenine metabolites such as kynurenic acid, 3-hydroxykynurenine,...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Rad Pour, Soudabeh, Morikawa, Hiromasa, Kiani, Narsis A., Gomez-Cabrero, David, Hayes, Alistair, Zheng, Xiaozhong, Pernemalm, Maria, Lehtiö, Janne, Mole, Damian J., Hansson, Johan, Eriksson, Hanna, Tegnér, Jesper
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017805/
https://ncbi.nlm.nih.gov/pubmed/32117720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00051
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