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The Role of a Voltage-Dependent Ca(2+) Channel Intracellular Linker: A Structure-Function Analysis

Voltage-dependent calcium channels (VDCCs) allow the passage of Ca(2+) ions through cellular membranes in response to membrane depolarization. The channel pore-forming subunit, α1, and a regulatory subunit (Ca(V)β) form a high affinity complex where Ca(V)β binds to a α1 interacting domain in the int...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Almagor, Lior, Chomsky-Hecht, Orna, Ben-Mocha, Adva, Hendin-Barak, Doran, Dascal, Nathan, Hirsch, Joel A.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6703595/
https://ncbi.nlm.nih.gov/pubmed/22649239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5727-11.2012
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