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Complement component 4 variations may influence psychopathology risk in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency

BACKGROUND: CYP21A2 defects result in congenital adrenal hyperplasia (CAH), an autosomal recessive disorder characterized by impaired adrenal steroidogenesis. CYP21A2 lies within the major histocompatibility complex in an area of the genome highly susceptible to genetic variation. Alterations in the...

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Detalhes bibliográficos
Publicado no:Hum Genet
Main Authors: Lao, Qizong, Jardin, Marcia Des, Jayakrishnan, Rahul, Ernst, Monique, Merke, Deborah
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6702947/
https://ncbi.nlm.nih.gov/pubmed/30465166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-018-1959-z
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