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Revisiting the association of HLA alleles and haplotypes with CYP21A2 mutations in a large cohort of patients with congenital adrenal hyperplasia

The CYP21A2 gene encoding 21-hydroxylase is on chromosome 6p21.3 within the human leukocyte antigen (HLA) class III major histocompatibility complex and an association between congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency and HLA class I and II alleles has been shown in genet...

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Detalhes bibliográficos
Publicado no:Gene
Main Authors: Jayakrishnan, Rahul, Lao, Qizong, Adams, Sharon D., Ward, William W., Merke, Deborah P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6702941/
https://ncbi.nlm.nih.gov/pubmed/30419250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2018.11.023
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