Targeting BCAA Catabolism to Treat Obesity-Associated Insulin Resistance

Recent studies implicate a strong association between elevated plasma branched-chain amino acids (BCAAs) and insulin resistance (IR). However, a causal relationship and whether interrupted BCAA homeostasis can serve as a therapeutic target for diabetes remain to be established experimentally. In thi...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Zhou, Meiyi, Shao, Jing, Wu, Cheng-Yang, Shu, Le, Dong, Weibing, Liu, Yunxia, Chen, Mengping, Wynn, R. Max, Wang, Jiqiu, Wang, Ji, Gui, Wen-Jun, Qi, Xiangbing, Lusis, Aldons J., Li, Zhaoping, Wang, Weiqing, Ning, Guang, Yang, Xia, Chuang, David T., Wang, Yibin, Sun, Haipeng
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2019
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6702639/
https://ncbi.nlm.nih.gov/pubmed/31167878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db18-0927
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