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Branched-Chain Amino Acid Negatively Regulates KLF15 Expression via PI3K-AKT Pathway

Recent studies have linked branched-chain amino acid (BCAA) with numerous metabolic diseases. However, the molecular basis of BCAA's roles in metabolic regulation remains to be established. KLF15 (Krüppel-like factor 15) is a transcription factor and master regulator of glycemic, lipid, and ami...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Front Physiol
Hauptverfasser: Liu, Yunxia, Dong, Weibing, Shao, Jing, Wang, Yibin, Zhou, Meiyi, Sun, Haipeng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661165/
https://ncbi.nlm.nih.gov/pubmed/29118722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00853
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