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Intraislet Ghrelin Signaling Does Not Regulate Insulin Secretion From Adult Mice
Exogenous ghrelin reduces glucose-stimulated insulin secretion and endogenous ghrelin protects against hypoglycemia during starvation. Islet ε-cells produce ghrelin and δ-cells express growth hormone secretagogue receptor (GHSR), suggesting the possibility of a paracrine mechanism for islet ghrelin...
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| Publicado en: | Diabetes |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Diabetes Association
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6702634/ https://ncbi.nlm.nih.gov/pubmed/31201280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db19-0079 |
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