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Metabolic control of T(H)17/iTreg balance by an epigenetic mechanism

Metabolism has been shown to integrate with epigenetics and transcription to modulate cell fate and function(1–3). Beyond meeting bioenergetic and biosynthetic demands to support T-cell differentiation(4–8), whether metabolism might control T-cell fate through epigenetic mechanism is unclear. Here t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nature
Hauptverfasser: Xu, Tao, Stewart, Kelly M., Wang, Xiaohu, Liu, Kai, Xie, Min, Ryu, Jae Kyu, Li, Ke, Ma, Tianhua, Wang, Haixia, Ni, Lu, Zhu, Saiyong, Cao, Nan, Zhu, Donwei, Zhang, Yu, Akassoglou, Katerina, Dong, Chen, Driggers, Edward M., Ding, Sheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6701955/
https://ncbi.nlm.nih.gov/pubmed/28783731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature23475
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