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A critical appraisal of the pathogenic protein spread hypothesis of neurodegeneration
There has been an explosion in the number of papers discussing the hypothesis of ‘pathogenic spread’ in neurodegenerative disease — the idea that abnormal forms of disease-associated proteins, such as tau or α-synuclein, physically move from neuron to neuron to induce disease progression. However, w...
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| Udgivet i: | Nat Rev Neurosci |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6701169/ https://ncbi.nlm.nih.gov/pubmed/26988744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrn.2016.13 |
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