Cholesterol-Induced Conformational Change in the Sphingomyelin Headgroup

Sphingomyelin (SM) and cholesterol (Cho) are the important lipids for the formation of biologically functional membrane domains, lipid rafts. However, the interaction between Cho and the headgroup of SM remains unclear. In this study, we performed solid-state NMR experiments to reveal the Cho effect...

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Pubblicato in:Biophys J
Autori principali: Hanashima, Shinya, Murakami, Kazuhiro, Yura, Michihiro, Yano, Yo, Umegawa, Yuichi, Tsuchikawa, Hiroshi, Matsumori, Nobuaki, Seo, Sangjae, Shinoda, Wataru, Murata, Michio
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2019
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6701000/
https://ncbi.nlm.nih.gov/pubmed/31303249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.06.019
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