Cholesterol-Induced Conformational Change in the Sphingomyelin Headgroup

Sphingomyelin (SM) and cholesterol (Cho) are the important lipids for the formation of biologically functional membrane domains, lipid rafts. However, the interaction between Cho and the headgroup of SM remains unclear. In this study, we performed solid-state NMR experiments to reveal the Cho effect...

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Vydáno v:Biophys J
Hlavní autoři: Hanashima, Shinya, Murakami, Kazuhiro, Yura, Michihiro, Yano, Yo, Umegawa, Yuichi, Tsuchikawa, Hiroshi, Matsumori, Nobuaki, Seo, Sangjae, Shinoda, Wataru, Murata, Michio
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6701000/
https://ncbi.nlm.nih.gov/pubmed/31303249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.06.019
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