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Cholesterol-Induced Conformational Change in the Sphingomyelin Headgroup

Sphingomyelin (SM) and cholesterol (Cho) are the important lipids for the formation of biologically functional membrane domains, lipid rafts. However, the interaction between Cho and the headgroup of SM remains unclear. In this study, we performed solid-state NMR experiments to reveal the Cho effect...

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Bibliographic Details
Published in:Biophys J
Main Authors: Hanashima, Shinya, Murakami, Kazuhiro, Yura, Michihiro, Yano, Yo, Umegawa, Yuichi, Tsuchikawa, Hiroshi, Matsumori, Nobuaki, Seo, Sangjae, Shinoda, Wataru, Murata, Michio
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6701000/
https://ncbi.nlm.nih.gov/pubmed/31303249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.06.019
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