Downregulation of mTOR Signaling Increases Stem Cell Population Telomere Length during Starvation of Immortal Planarians

Reduction of caloric intake delays and prevents age-associated diseases and extends the life span in many organisms. It may be that these benefits are due to positive effects of caloric restriction on stem cell function. We use the planarian model Schmidtea mediterranea, an immortal animal that adap...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Stem Cell Reports
Prif Awduron: Iglesias, Marta, Felix, Daniel A., Gutiérrez-Gutiérrez, Óscar, De Miguel-Bonet, Maria del Mar, Sahu, Sounak, Fernández-Varas, Beatriz, Perona, Rosario, Aboobaker, A. Aziz, Flores, Ignacio, González-Estévez, Cristina
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700675/
https://ncbi.nlm.nih.gov/pubmed/31353226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.06.005
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