Downregulation of mTOR Signaling Increases Stem Cell Population Telomere Length during Starvation of Immortal Planarians

Reduction of caloric intake delays and prevents age-associated diseases and extends the life span in many organisms. It may be that these benefits are due to positive effects of caloric restriction on stem cell function. We use the planarian model Schmidtea mediterranea, an immortal animal that adap...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Iglesias, Marta, Felix, Daniel A., Gutiérrez-Gutiérrez, Óscar, De Miguel-Bonet, Maria del Mar, Sahu, Sounak, Fernández-Varas, Beatriz, Perona, Rosario, Aboobaker, A. Aziz, Flores, Ignacio, González-Estévez, Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700675/
https://ncbi.nlm.nih.gov/pubmed/31353226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.06.005
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