Ras Downstream Effector GGCT Alleviates Oncogenic Stress

How cells adapt to oncogenic transformation-associated cellular stress and become fully transformed is still unknown. Here we identified a novel GGCT-regulated glutathione (GSH)-reactive oxygen species (ROS) metabolic pathway in oncogenic stress alleviation. We identified GGCT as a target of oncogen...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: He, Zaoke, Wang, Shixiang, Shao, Yuanyuan, Zhang, Jing, Wu, Xiaolin, Chen, Yuxing, Hu, Junhao, Zhang, Feng, Liu, Xue-Song
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700472/
https://ncbi.nlm.nih.gov/pubmed/31400748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.07.036
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