Hyperactivation of EGFR and downstream effector phospholipase D1 by oncogenic FAM83B

Despite the progress made in targeted anticancer therapies in recent years, challenges remain. The identification of new potential targets will ensure that the arsenal of cancer therapies continues to expand. FAM83B was recently discovered in a forward genetic screen for novel oncogenes that drive h...

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Autori principali: Cipriano, Rocky, Bryson, Benjamin L., Miskimen, Kristy L.S., Bartel, Courtney A., Hernandez-Sanchez, Wilnelly, Bruntz, Ronald C., Scott, Sarah A., Lindsley, Craig W., Brown, H. Alex, Jackson, Mark W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923847/
https://ncbi.nlm.nih.gov/pubmed/23912460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.293
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