FAM83B mediates EGFR- and RAS-driven oncogenic transformation

Aberrant regulation of growth signaling is a hallmark of cancer development that often occurs through the constitutive activation of growth factor receptors or their downstream effectors. Using validation-based insertional mutagenesis (VBIM), we identified family with sequence similarity 83, member...

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Detalhes bibliográficos
Main Authors: Cipriano, Rocky, Graham, James, Miskimen, Kristy L.S., Bryson, Benjamin L., Bruntz, Ronald C., Scott, Sarah A., Brown, H. Alex, Stark, George R., Jackson, Mark W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428078/
https://ncbi.nlm.nih.gov/pubmed/22886302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI60517
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