TIGAR Attenuates High Glucose-Induced Neuronal Apoptosis via an Autophagy Pathway

Hyperglycemia-induced neuronal apoptosis is one of the important reasons for diabetic neuropathy. Long-time exposure to high glucose accelerates many aberrant glucose metabolic pathways and eventually leads to neuronal injury. However, the underlying mechanisms of metabolic alterations remain unknow...

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Bibliographic Details
Published in:Front Mol Neurosci
Main Authors: Zhou, Wenjuan, Yao, Yuan, Li, Jinxing, Wu, Dong, Zhao, Man, Yan, Zongting, Pang, Aimei, Kong, Liang
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700368/
https://ncbi.nlm.nih.gov/pubmed/31456661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2019.00193
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