Decitabine Downregulates TIGAR to Induce Apoptosis and Autophagy in Myeloid Leukemia Cells

Decitabine (DAC) is a well-known DNA methyltransferase inhibitor, which has been widely used for the treatment of acute myeloid leukemia (AML). However, in addition to hypomethylation, DAC in AML is also involved in cell metabolism, apoptosis, and immunity. The TP53-induced glycolysis and apoptosis...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oxid Med Cell Longev
Egile Nagusiak: Li, Lanzhu, Liu, Wenjie, Sun, Qian, Zhu, Han, Hong, Ming, Qian, Sixuan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Hindawi 2021
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7836025/
https://ncbi.nlm.nih.gov/pubmed/33532040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/8877460
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak