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Second-generation EGFR and ErbB tyrosine kinase inhibitors as first-line treatments for non-small cell lung cancer

The discovery that mutations in the EGFR gene are present in up to 50% of patients with lung adenocarcinoma, and the development of highly efficacious EGFR tyrosine kinase inhibitors (TKIs), has revolutionized the way this common malignancy is treated. Three generations of EGFR TKIs are now approved...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Wang, Shouzheng, Li, Junling
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700283/
https://ncbi.nlm.nih.gov/pubmed/31496745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S198945
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