Multi-Compartment Profiling of Bacterial and Host Metabolites Identifies Intestinal Dysbiosis and Its Functional Consequences in the Critically Ill Child

OBJECTIVES: Adverse physiology and antibiotic exposure devastate the intestinal microbiome in critical illness. Time and cost implications limit the immediate clinical potential of microbial sequencing to identify or treat intestinal dysbiosis. Here, we examined whether metabolic profiling is a feas...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Crit Care Med
Main Authors: Wijeyesekera, Anisha, Wagner, Josef, De Goffau, Marcus, Thurston, Sarah, Rodrigues Sabino, Adilson, Zaher, Sara, White, Deborah, Ridout, Jenna, Peters, Mark J., Ramnarayan, Padmanabhan, Branco, Ricardo G., Torok, M. Estee, Valla, Frederic, Meyer, Rosan, Klein, Nigel, Frost, Gary, Parkhill, Julian, Holmes, Elaine, Pathan, Nazima
פורמט: Artigo
שפה:Inglês
יצא לאור: Lippincott Williams & Wilkins 2019
נושאים:
Online Clinical Investigations
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6699985/
https://ncbi.nlm.nih.gov/pubmed/31169619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000003841
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