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Tau isoform–specific stabilization of intermediate states during microtubule assembly and disassembly

The microtubule (MT)-associated protein tau regulates the critical growing and shortening behaviors of MTs, and its normal activity is essential for neuronal development and maintenance. Accordingly, aberrant tau action is tightly associated with Alzheimer's disease and is genetically linked to...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Best, Rebecca L., LaPointe, Nichole E., Liang, Jiahao, Ruan, Kevin, Shade, Madeleine F., Wilson, Leslie, Feinstein, Stuart C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6699843/
https://ncbi.nlm.nih.gov/pubmed/31266806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009124
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