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Improving Editing Efficiency for the Sequences with NGH PAM Using xCas9-Derived Base Editors
The development of CRISPR/Cas9-mediated base editors (BEs) provided a versatile tool for precise genome editing. The recently developed xCas9-derived base editors (xBEs) that recognize the NG PAM substantially expand the targeting scope in the genome, while their editing efficiency needs to be impro...
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| Izdano u: | Mol Ther Nucleic Acids |
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| Glavni autori: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society of Gene & Cell Therapy
2019
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6699141/ https://ncbi.nlm.nih.gov/pubmed/31400605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.06.024 |
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