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Circular zymogens of human ribonuclease 1

The endogenous production of enzymes as zymogens provides a means to control catalytic activities. Here, we describe the heterologous production of ribonuclease 1 (RNase 1), which is the most prevalent secretory ribonuclease in humans, as a zymogen. In folded RNase 1, the N and C termini flank the e...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Protein Sci
Päätekijät: Windsor, Ian W., Graff, Crystal J., Raines, Ronald T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley & Sons, Inc. 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6699097/
https://ncbi.nlm.nih.gov/pubmed/31306518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3686
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