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Design and Characterization of an HIV-Specific Ribonuclease Zymogen
Ribonucleases are evoking medical interest because of their intrinsic cytotoxic activity. Most notably, ranpirnase, which is an amphibian ribonuclease, is in advanced clinical trials as a chemotherapeutic agent for the treatment of cancer. Here, we describe a strategy to create a novel antiviral age...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc.
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2888699/ https://ncbi.nlm.nih.gov/pubmed/19025416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2008.0146 |
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