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A Drosophila cell-free system that senses DNA breaks and triggers phosphorylation signalling

Preblastoderm Drosophila embryo development is characterized by fast cycles of nuclear divisions. Extracts from these embryos can be used to reconstitute complex chromatin with high efficiency. We now discovered that this chromatin assembly system contains activities that recognize unprotected DNA e...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Harpprecht, Lisa, Baldi, Sandro, Schauer, Tamas, Schmidt, Andreas, Bange, Tanja, Robles, Maria S, Kremmer, Elisabeth, Imhof, Axel, Becker, Peter B
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6698661/
https://ncbi.nlm.nih.gov/pubmed/31147711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz473
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